Videos, Clinical Studies and Medical Journal Articles for Acute and Chronic and Pancreatitis, Total Pancreatectomy with Auto Islet Transplant (TP/AIT or TP/IAT), Sphincter of Oddi Dysfunction (SOD), ERCP, EUS and Treatment:
- Watch this video of Dr. Sutherland to learn more about the function of the pancreas and how surgery can help people who have chronic pancreatitis or complications from type 1 diabetes. Dr. Sutherland also explains the evaluation process to identify potential candidates for surgery.
- View clinical study article of 2012, Total Pancreatectomy and Islet Autotransplantation for Chronic Pancreatitis by David E.R. Sutherland* from University of Minnesota. Discusses some of the causes of chronic pancreatitis such as idiopathic, hereditary, genetic, biliary lithiasis, pancreatic divisum, sphincter of Oddi dysfunction, trauma, alcohol, pseudocys, small, dilated or blocked ducts, and pancreatic or duct stones. Reviews history of TP/AIT, success rates, options, criteria and testing, and details about the surgery. *Melena Bellin, Juan J. Blondet, Greg J. Beilman, Ty B. Dunn, Srinath Chinnakotla, Timothy L. Pruett, Martin L. Freeman, A.N. Balamurugan, Barbara Bland, David Radosevich and Bernhard J. Hering.
- View study of August 2010, Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant, University of Minnesota – Clinical and Translational Science Institute. (This is the study I’m currently taking part in). To test the effects of sitagliptin on the need for insulin (the hormone that lowers blood sugars) by patients who receive a pancreatectomy and islet autotransplant for chronic pancreatitis. At the current time, about one-third of patients are insulin independent (do not need to take insulin) after autotransplant, but the other two-thirds still need some insulin. Sitagliptin works by increasing the amount of a hormone called glucagon-like peptide 1, or GLP-1, in the body which then increases the amount of insulin that is made by the beta cells (the insulin producing cell of the islets). GLP-1 might also help protect beta cells from dying under stressful conditions and increase the production of new beta cells. The primary goal of this study is to see if taking sitagliptin for one year after islet autotransplant increases the number of patients who achieve and maintain insulin independence. Other goals of this study are to see if sitagliptin reduces the amount of insulin injections needed or helps the islets make more insulin.
- Watch Livestream broadcast video of Nov. 2011, Dr. David E. R. Sutherland and Dr. Melena Bellin covering pancreatitis, diabetes and the Total Pancreatectomy with Auto Islet Transplant from University of Minnesota Medical Center, Fairview and University of Minnesota Amplatz Children’s Hospital covered by Kids Who Care Foundation.
- Watch video of Aug. 2011, Dr. Melena Bellin - Quality of Life Improves for Pediatric Patients After Total Pancreatectomy and Islet Autotransplant for Chronic Pancreatitis from University of Minnesota Amplatz Children’s Hospital.
- View article of 2011, Pediatric Pancreatectomy and Islet Auto-Transplant Program information from University of Minnesota Medical Center, Fairview and University of Minnesota Amplatz Children’s Hospital. Information on pediatric chronic pancreatitis treatment.
- View video of Dec. 2010, Dr. Katherine Morgan as she discusses how the Auto Islet Transplant works at Medical University of South Carolina (MUSC). Hear from patient Sarah Gibbins.
- Listen to Podcast of Dr. Cotton as he talks about sphincter of Oddi dysfunction and a clinical study. (View the written interview.) Dr. Cotton, founder of MUSC Digestive Disease Center, gives insight on sphincter of Oddi disease and treatment.
- View study of May 2008, Evaluating Predictors & Interventions in Sphincter of Oddi Dysfunction (SOD) EPISOD – Clinical study for SOD III patients. Clinical study done at Minnesota: University of Minnesota, South Carolina: Medical University of South Carolina Digestive Disease Center, Indiana: Indiana University, Texas: Methodist Dallas Medical Center, California: Cedars Sinai Medical Center, Connecticut: Yale University, Washington: Virginia Mason Medical Center or Missouri: Midwest Therapeutic Endoscopy Consultants.
- View medical journal article of March 2010, Practical Gastroenterology – Sphincter of Oddi Dysfunction (SOD) by Abhijit Kulkarn, Disease of the Billiary Tract, Series 2 – Rad M. Agrawal, M.D., Series Editor. Covers introduction, classification, diagnosis, diagnostic method and therapy of SOD.
- View clinical article of 2009, Gastrointestinal Endoscopy – EUS-based Criteria for the Diagnosis of Chronic Pancreatitis: The Rosemont Classification by Marc F. Catalano, MD; Anand Sahai, MD; Michael Levy, MD; Joseph Romagnuolo, MD; Maurits Wiersema, MD; William Brugge, MD; Martin Freeman, MD; Kenji Yamao, MD; Marcia Canto, MD; Lyndon V. Hernandez, MD.
- View clinical medical article of June 2008, Minnesota Medical – Approach to Acute, Recurrent, and Chronic Pancreatitis by Timothy P. Kinney, M.D., and Martin L. Freeman, M.D. Covers Diagnosing Pancreatitis, Acute Pancreatitis, Autoimmune Pancreatitis, Microlithiasis and Occult Gallstones, Sphincter of Oddi Dysfunction, Pancreas Divisum, Tumors, Rare Causes, Chronic Pancreatitis.
- View medical journal of 2006, American Journal of Gastroenterology – Practice Guidelines in Acute Pancreatitis by Peter A. Banks, M.D., M.A.C.G.; Martin L. Freeman, M.D., F.A.C.G.; and the Practice Parameters Committee of the American College of Gastroenterology. A review of clinical results of acute pancreatitis.
